为何减肥成果如此难维持？

jacky

We know that 80% of the obese people who lose weight, gain most of it back within a few years. Is it because they lack the discipline or is there a physiological mechanism beyond their control that is driving the weight back.

Your body weigh is regulated by your barin.  There are numerous hormones in your body that controls your appetite to keep body weight within a certain range.
Leptin:  Leptin - one of the most important hormones-  is primarily produced from fat cells and it's circulating level is directly proportional to body fat levels.

Ghrelin: Ghrelin is released from the stomach and its primary purpose is it stimulates hunger,

Cholecystokinin(CKK): CKK is another intestinal which suppresses appetite.

Eating less causes an increase in profound reductions in energy expenditure and levels of leptin and cholecystokinin and increases in ghrelin and appetite all of which promote weight regain.
What was the study purpose?The purpose of the study was to see whether these fluctuations in  these appetite regulating hormones persists with prolonged maintenance of reduced weight.If it persists, it maybe be one of the reasons why people gain back weight so easily.
What was the sudy design?The study involved 50 overweight or obese participants in a 10 week weight loss program. They measured different hormones and appetite levels before the weight loss, after the weight loss (10 weeks) and after 62 weeks of weight maintenance.
What were the results?The mean weight loss was around 26 lbs after 10 weeks.  There was significant changes in hormones  and appetite after weight loss, and all these changes persisted even after 62 weeks.

The figure shows that hunger and desire to eat were significantly higher after 10 weeks and 62 weeks from the baseline. In short, It just means that body is trying to get back to the  baseline weight.
ConclusionsThere are multiple physiological compensatory mechanisms vigorously resisting weight loss  in obese and overweight people.You didn't gain the weight back just because 'life got busy' or you lacked the will power


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